[Slaam] SLAAM Seminar May 20 Linnea Lemma (Princeton)

[SLAAM Distribution List]

Dear enthusiasts of the SLAAM seminars,



We are excited to announce that the next Soft Living Active and Adaptive Matter (SLAAM)<https://physics.ucmerced.edu/slaam> seminar will be given by Dr. Linnea Lemma (Princeton) on Monday, May 20, at 9am Pacific/11am Central/12 noon Eastern time (US), with the title:



Driven protein fluxes control the number, size, and position of an essential phase-separated organelle in algae



Please join at the link below to attend:
https://weizmann.zoom.us/j/97695755224?pwd=YjNEc0NEbVF0L0grb25HYWk4UDEyUT09

Meeting ID: 976 9575 5224<tel:9575%205224> Password: 383132

There will be a brief Q&A session at the end of the hour. Graduate students will have an opportunity to interact with the speaker in an informal setting during the "Meet the speaker" timeslot just after the talk.



Please see more info here or in the flyer in the text below:

Abstract: Phase separation of biological molecules has emerged as a key mechanism by which cells organize their components. Investigating the physical principles by which these biomolecular condensates facilitate cellular functions, which are generically out-of-equilibrium, remains a grand challenge at the intersection of statistical physics and cell biology. The inherent complexity of biological systems has posed a significant obstacle to conceptual progress in this field. We leverage the algal pyrenoid—an experimentally tractable condensate responsible for 30% of global CO2 fixation—as a powerful model system. Notably, during cell division, the pyrenoid, consisting of the CO2 -fixing enzyme Rubisco and the linker protein EPYC1, undergoes rapid dissolution and recondensation. We identify a kinase, KEY1, that regulates pyrenoid dissolution and proves to be essential for maintaining pyrenoid number, size, and function. We develop a minimal mathematical model of kinase activity that recapitulates the dynamic behaviors seen in vivo and suggests how molecular fluxes driven by kinase activity can robustly control condensate formation and localization.

Speaker bio: Linnea Lemma is an experimental physicist who seeks to uncover the physical principles governing intracellular organization. She is particularly interested in the out-of-equilibrium processes that underlie biological functions.
Linnea is currently a HHMI Hanna H. Gray Fellow working at Princeton University with Ned Wingreen, Martin Jonikas and Clifford Brangwynne. She obtained her PhD in active matter physics from Brandeis University.



Hope to see you there!



Best regards,
Alexandra Tayar

on behalf of the SLAAM organizing team
(Daniel Beller, Suraj Shankar, Kinjal Dasbiswas)

To join the SLAAM mailing list, please sign up here<https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCkEAzTrQzNpQi-P59LZiKL_lMA3briJm9KQh9Y3suN&s=3hc1lEhiJwBLtMEr12Z9K5XtZaVlEfOZKYXGtXCjRDg&e=>. If you’re a postdoc interested in giving a SLAAM talk, we invite you to register your interest on that webform.





Alexandra Tayar
Assistant Professor
Department of chemical and biological physics
Weizmann Institute of science
Tayar Lab<https://www.weizmann.ac.il/chembiophys/tayar/home>


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