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<blockquote type="cite" class=""><span style="font-size: small; -webkit-tap-highlight-color: transparent; -webkit-text-size-adjust: 100%;">Dear enthusiasts of the SLAAM seminars,</span><br>
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<div class="" style="margin:0in"><font size="2" class=""><span class="x_x_x_contentpasted0">We are excited to announce that the next <a href="https://physics.ucmerced.edu/slaam" data-auth="NotApplicable" title="https://physics.ucmerced.edu/slaam" class="" style="color:rgb(5,99,193)">Soft
Living Active and Adaptive Matter (SLAAM)</a> seminar will be given by <b class="">Dr. </b></span><b class="">Linnea <span class="x_x_x_apple-converted-space">Lemma </span></b>(Princeton)<span class="x_x_x_apple-converted-space"> </span><span class="x_x_x_contentpasted0">on <b class="">Monday, May
20, </b>at <b class="">9am Pacific/11am Central/12 noon Eastern time (US)</b>, with the title:</span></font></div>
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<div class="" style="margin:0in; background-color:white"><b class=""><font size="2" class="">Driven protein fluxes control the number, size, and position of an essential phase-separated organelle in algae</font></b></div>
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<div class="" style="margin:0in; background-color:white"><span class="x_x_x_contentpasted0"><font size="2" class="">Please join at the link below to attend:</font></span></div>
<div class="" style="margin:0in; background-color:white"><a href="https://weizmann.zoom.us/j/97695755224?pwd=YjNEc0NEbVF0L0grb25HYWk4UDEyUT09" data-auth="NotApplicable" class=""><font size="2" class="">https://weizmann.zoom.us/j/97695755224?pwd=YjNEc0NEbVF0L0grb25HYWk4UDEyUT09</font></a></div>
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<div class=""><font size="2" class="">Meeting ID: 976 <a href="tel:9575 5224">9575 5224</a> Password: 383132</font></div>
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<div class="" style="margin:0in"><font size="2" class="">There will be a brief Q&A session at the end of the hour. Graduate students will have an opportunity to interact with the speaker in an informal setting during the "Meet the speaker" timeslot just after
the talk.<span class="x_x_x_apple-converted-space"> </span></font></div>
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<div class="" style="margin:0in; background-color:white"><span class="" style="color:rgb(36,36,36)"><font size="2" class="">Please see more info </font></span>here<span class="" style="color:rgb(36,36,36)"><font size="2" class=""> or in the flyer<span class="x_x_x_apple-converted-space"> </span>in
the text below:</font></span></div>
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<font size="2" class=""><span class="x_x_x_contentpasted0"><b class="">Abstract</b></span><span class="x_x_x_contentpasted0">: </span>Phase separation of biological molecules has emerged as a key mechanism by which cells organize their components. Investigating
the physical principles by which these biomolecular condensates facilitate cellular functions, which are generically out-of-equilibrium, remains a grand challenge at the intersection of statistical physics and cell biology. The inherent complexity of biological
systems has posed a significant obstacle to conceptual progress in this field. We leverage the algal pyrenoid—an experimentally tractable condensate responsible for 30% of global CO2 fixation—as a powerful model system. Notably, during cell division, the pyrenoid,
consisting of the CO2 -fixing enzyme Rubisco and the linker protein EPYC1, undergoes rapid dissolution and recondensation. We identify a kinase, KEY1, that regulates pyrenoid dissolution and proves to be essential for maintaining pyrenoid number, size, and
function. We develop a minimal mathematical model of kinase activity that recapitulates the dynamic behaviors seen in vivo and suggests how molecular fluxes driven by kinase activity can robustly control condensate formation and localization.</font></p>
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<div class="" style="margin:0in; background-color:white"><font size="2" class=""><b class="">Speaker bio:<span class="x_x_x_apple-converted-space"> </span></b>Linnea Lemma is an experimental physicist who seeks to uncover the physical principles governing intracellular
organization. She is particularly interested in the out-of-equilibrium processes that underlie biological functions. </font></div>
<div class="" style="margin:0in; background-color:white"><font size="2" class="">Linnea is currently a HHMI Hanna H. Gray Fellow working at Princeton University with Ned Wingreen, Martin Jonikas and Clifford Brangwynne. She obtained her PhD in active matter
physics from Brandeis University. </font></div>
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<div class="" style="margin:0in; background-color:white"><span class="x_x_x_contentpasted0"><font size="2" class="">Hope to see you there! </font></span></div>
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<div class="" style="margin:0in; background-color:white"><span class="x_x_x_contentpasted0"><font size="2" class="">Best regards,</font></span></div>
<div class="" style="margin:0in; background-color:white"><span class="x_x_x_contentpasted0"><font size="2" class="">Alexandra Tayar</font></span></div>
<p class="" style="margin-bottom:12pt; background-color:white"><font size="2" class=""><span class="x_x_x_contentpasted0">on behalf of the SLAAM organizing team</span><br class="">
<span class="x_x_x_contentpasted0">(Daniel Beller, Suraj Shankar, Kinjal Dasbiswas)</span></font></p>
<div class="" style="margin:0in; background-color:white"><span class="x_x_x_contentpasted0"><i class=""><font size="2" class="">To join the SLAAM mailing list, please sign up <a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCkEAzTrQzNpQi-P59LZiKL_lMA3briJm9KQh9Y3suN&s=3hc1lEhiJwBLtMEr12Z9K5XtZaVlEfOZKYXGtXCjRDg&e=" data-auth="NotApplicable" title="https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCk" class="" style="color:rgb(5,99,193)">here</a>. If
you’re a postdoc interested in giving a SLAAM talk, we invite you to register your interest on that webform.</font></i></span></div>
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<div class="" style="margin:0in"><span class="" style="font-size:small">Alexandra Tayar</span></div>
<div class="" style="margin:0in"><span class="" style="font-size:small">Assistant Professor</span></div>
<div class="" style="margin:0in"><font size="2" class="">Department of chemical and biological physics</font></div>
<div class="" style="margin:0in"><span class="" style="font-size:small">Weizmann Institute of science</span></div>
<div class="" style="margin:0in"><a href="https://www.weizmann.ac.il/chembiophys/tayar/home" data-auth="NotApplicable" class="">Tayar Lab</a><span class="" style="font-size:small"> </span></div>
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