[Slaam] SLAAM Seminar Monday, Sep 12: Krishna Shrinivas (Harvard Univ.)

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Wed Sep 7 15:14:23 PDT 2022


interested

 

From: Slaam <slaam-bounces at lists.ucmerced.edu> On Behalf Of SLAAM
Distribution List
Sent: September 7, 2022 4:22 PM
To: slaam at lists.ucmerced.edu
Subject: [Slaam] SLAAM Seminar Monday, Sep 12: Krishna Shrinivas (Harvard
Univ.)

 

Dear enthusiasts of the SLAAM seminars,

 

We invite you to join us for the next Soft Living Active and Adaptive Matter
(SLAAM) seminar, to be given by Dr. Krishna Shrinivas (Harvard University)
on Monday, Sep 12 at 9 am Pacific/12 noon Eastern time.

 

Title: The many phases of a cell 

 [flyer
<https://physics.ucmerced.edu/sites/physics.ucmerced.edu/files/page/document
s/krishna_shrinivas_slaam70.pdf> ]

 

The Zoom information for this talk is:

https://ucmerced.zoom.us/j/92693607475?pwd=TnI5dDhRRnYvejNZK2xNN0s4M0R5UT09

Meeting ID: 926 9360 7475

Passcode: 223642

 

As usual, there will be a 15 min informal Q&A at the end of the hour.
Graduate students will have an opportunity to interact with the speaker in
an informal setting during the "Meet the speaker" timeslot just after the
talk. Please join if the time works for you. Please sign up here
<https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_
d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=
DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfW
Q&m=NK4EGo1VvrDiYSxdvOUJXgCkEAzTrQzNpQi-P59LZiKL_lMA3briJm9KQh9Y3suN&s=3hc1l
EhiJwBLtMEr12Z9K5XtZaVlEfOZKYXGtXCjRDg&e=>  to register your interest to
give a talk (postdocs only) and to receive these notifications.

 

Abstract: 

Cells are a remarkable example of multiphase living fluids  - billions of
proteins and nucleic acids self-organize by phase transitions into diverse
coexisting assemblies called biomolecular condensates. How dozens of
interacting species in complex environments and subject to non-equilibrium
fluxes encode for macroscopic properties remains challenging to decipher. In
this talk, I will introduce a framework to predict emergent behavior in
multiphase living fluids - drawing on ideas across non-equilibrium theory,
statistical physics, and applied mathematics. By integrating phase-field
simulations and random-matrix theory, I will first describe a model of
fluids with randomly interacting components that exhibits complex yet
surprisingly predictable multiphase coexistence. I will subsequently
describe how active chemical fluxes can tunably modify emergent phase
behavior, even in the absence of compositional changes. Finally, when
interactions are partially structured i.e. non-random, I will show that
there are statistical constraints on number of steady-state properties. I
will conclude by highlighting few open questions and exciting future
directions at the intersection of biomolecular condensates and soft living
matter.

About the speaker: 

Dr. Krishna Shrinivas is an interdisciplinary scientist with broad interests
in biophysics and soft matter, with an emphasis on investigating
self-organization in cell biology. Towards this, he develops quantitative
theoretical and computational frameworks and collaborates extensively with
diverse experimental scientists. Dr. Shrinivas is currently an Independent
Fellow of Quantitative Biology at Harvard University, jointly funded by NSF
and the Simons Foundation. He previously trained as a chemical engineer,
completing his PhD at MIT working with Arup K. Chakraborty and his B.Tech
(Honors) at IIT-Madras.


Best regards,

Dan Beller

on behalf of the SLAAM organizing team

 

 

Daniel Beller

Assistant Professor

Department of Physics and Astronomy

Johns Hopkins University

pages.jh.edu/dbeller3

(he/him/his)

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