[Slaam] SLAAM Seminar Monday, Sep 12: Krishna Shrinivas (Harvard Univ.)
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Wed Sep 7 13:22:00 PDT 2022
Dear enthusiasts of the SLAAM seminars,
We invite you to join us for the next Soft Living Active and Adaptive Matter (SLAAM) seminar, to be given by Dr. Krishna Shrinivas (Harvard University) on Monday, Sep 12 at 9 am Pacific/12 noon Eastern time.
Title: The many phases of a cell
[flyer<https://physics.ucmerced.edu/sites/physics.ucmerced.edu/files/page/documents/krishna_shrinivas_slaam70.pdf>]
The Zoom information for this talk is:
https://ucmerced.zoom.us/j/92693607475?pwd=TnI5dDhRRnYvejNZK2xNN0s4M0R5UT09
Meeting ID: 926 9360 7475
Passcode: 223642
As usual, there will be a 15 min informal Q&A at the end of the hour. Graduate students will have an opportunity to interact with the speaker in an informal setting during the "Meet the speaker" timeslot just after the talk. Please join if the time works for you. Please sign up here<https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCkEAzTrQzNpQi-P59LZiKL_lMA3briJm9KQh9Y3suN&s=3hc1lEhiJwBLtMEr12Z9K5XtZaVlEfOZKYXGtXCjRDg&e=> to register your interest to give a talk (postdocs only) and to receive these notifications.
Abstract:
Cells are a remarkable example of multiphase living fluids - billions of proteins and nucleic acids self-organize by phase transitions into diverse coexisting assemblies called biomolecular condensates. How dozens of interacting species in complex environments and subject to non-equilibrium fluxes encode for macroscopic properties remains challenging to decipher. In this talk, I will introduce a framework to predict emergent behavior in multiphase living fluids - drawing on ideas across non-equilibrium theory, statistical physics, and applied mathematics. By integrating phase-field simulations and random-matrix theory, I will first describe a model of fluids with randomly interacting components that exhibits complex yet surprisingly predictable multiphase coexistence. I will subsequently describe how active chemical fluxes can tunably modify emergent phase behavior, even in the absence of compositional changes. Finally, when interactions are partially structured i.e. non-random, I will show that there are statistical constraints on number of steady-state properties. I will conclude by highlighting few open questions and exciting future directions at the intersection of biomolecular condensates and soft living matter.
About the speaker:
Dr. Krishna Shrinivas is an interdisciplinary scientist with broad interests in biophysics and soft matter, with an emphasis on investigating self-organization in cell biology. Towards this, he develops quantitative theoretical and computational frameworks and collaborates extensively with diverse experimental scientists. Dr. Shrinivas is currently an Independent Fellow of Quantitative Biology at Harvard University, jointly funded by NSF and the Simons Foundation. He previously trained as a chemical engineer, completing his PhD at MIT working with Arup K. Chakraborty and his B.Tech (Honors) at IIT-Madras.
Best regards,
Dan Beller
on behalf of the SLAAM organizing team
Daniel Beller
Assistant Professor
Department of Physics and Astronomy
Johns Hopkins University
pages.jh.edu/dbeller3
(he/him/his)
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