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<div style="font-size: 9.75pt;">Dear enthusiasts of the SLAAM seminars,</div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="margin: 0in; font-size: 13px;">We are excited to announce that the next
<span style="color: rgb(5, 99, 193);"><a href="https://physics.ucmerced.edu/slaam" id="OWA0978271b-04a8-cfbb-7519-510f1b411d87" class="OWAAutoLink" title="https://physics.ucmerced.edu/slaam" data-auth="NotApplicable" data-loopstyle="linkonly" style="color: rgb(5, 99, 193);">Soft
Living Active and Adaptive Matter (SLAAM)</a></span> seminar will be given by <b>
Dr. Linnea Lemma </b>(Princeton) on <b>Monday, May 20, </b>at <b>9am Pacific/11am Central/12 noon Eastern time (US)</b>, with the title:</div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px; color: rgb(36, 36, 36);"> </span></p>
<div style="background-color: white; margin: 0in; font-size: 13px;"><b>Driven protein fluxes control the number, size, and position of an essential phase-separated organelle in algae</b></div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="background-color: white; margin: 0in; font-size: 13px;">Please join at the link below to attend:</div>
<div style="background-color: white; margin: 0in; font-size: 13px;"><a href="https://weizmann.zoom.us/j/97695755224?pwd=YjNEc0NEbVF0L0grb25HYWk4UDEyUT09" id="OWA4cbedfa8-530a-2130-b36a-6e8067d60889" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly">https://weizmann.zoom.us/j/97695755224?pwd=YjNEc0NEbVF0L0grb25HYWk4UDEyUT09</a></div>
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<div style="font-size: 13px;">Meeting ID: 976 <a href="tel:9575 5224" id="OWA99e68668-c19c-7031-6abd-4e8ff5f82408" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly">
9575 5224</a> Password: 383132</div>
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<div style="margin: 0in; font-size: 13px;">There will be a brief Q&A session at the end of the hour. Graduate students will have an opportunity to interact with the speaker in an informal setting during the "Meet the speaker" timeslot just after the talk. </div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="background-color: white; margin: 0in;"><span style="font-size: 13px; color: rgb(36, 36, 36);">Please see more info
</span>here<span style="font-size: 13px; color: rgb(36, 36, 36);"> or in the flyer in the text below:</span></div>
<p style="background-color: white; margin-right: 0in; margin-left: 0in;"><span style="font-size: 13px;"><b>Abstract</b>: Phase separation of biological molecules has emerged as a key mechanism by which cells organize their components. Investigating the physical
principles by which these biomolecular condensates facilitate cellular functions, which are generically out-of-equilibrium, remains a grand challenge at the intersection of statistical physics and cell biology. The inherent complexity of biological systems
has posed a significant obstacle to conceptual progress in this field. We leverage the algal pyrenoid—an experimentally tractable condensate responsible for 30% of global CO2 fixation—as a powerful model system. Notably, during cell division, the pyrenoid,
consisting of the CO2 -fixing enzyme Rubisco and the linker protein EPYC1, undergoes rapid dissolution and recondensation. We identify a kinase, KEY1, that regulates pyrenoid dissolution and proves to be essential for maintaining pyrenoid number, size, and
function. We develop a minimal mathematical model of kinase activity that recapitulates the dynamic behaviors seen in vivo and suggests how molecular fluxes driven by kinase activity can robustly control condensate formation and localization.</span></p>
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<div style="background-color: white; margin: 0in; font-size: 13px;"><b>Speaker bio:
</b>Linnea Lemma is an experimental physicist who seeks to uncover the physical principles governing intracellular organization. She is particularly interested in the out-of-equilibrium processes that underlie biological functions. </div>
<div style="background-color: white; margin: 0in; font-size: 13px;">Linnea is currently a HHMI Hanna H. Gray Fellow working at Princeton University with Ned Wingreen, Martin Jonikas and Clifford Brangwynne. She obtained her PhD in active matter physics from
Brandeis University. </div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="background-color: white; margin: 0in; font-size: 13px;">Hope to see you there! </div>
<p style="background-color: white; margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="background-color: white; margin: 0in; font-size: 13px;">Best regards,</div>
<div style="background-color: white; margin: 0in; font-size: 13px;">Alexandra Tayar</div>
<p style="background-color: white; margin-bottom: 12pt;"><span style="font-size: 13px;">on behalf of the SLAAM organizing team<br>
(Daniel Beller, Suraj Shankar, Kinjal Dasbiswas)</span></p>
<div style="background-color: white; margin: 0in; font-size: 13px;"><i>To join the SLAAM mailing list, please sign up
</i><span style="color: rgb(5, 99, 193);"><i><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCkEAzTrQzNpQi-P59LZiKL_lMA3briJm9KQh9Y3suN&s=3hc1lEhiJwBLtMEr12Z9K5XtZaVlEfOZKYXGtXCjRDg&e=" id="OWAbc90568b-37b4-32d7-91ec-6b524dea5710" class="OWAAutoLink" title="https://urldefense.proofpoint.com/v2/url?u=https-3A__docs.google.com_forms_d_e_1FAIpQLScTyzEuuE7TfrrapgP4tzN-5FoPSqbBhURUxa9-2Dzc8USnY1IPzA_viewform&d=DwMFAw&c=WO-RGvefibhHBZq3fL85hQ&r=6T170XR90Za4-nl9r1e8-WfEJbvH5g5hJbA9UumqfWQ&m=NK4EGo1VvrDiYSxdvOUJXgCk" data-auth="NotApplicable" data-loopstyle="linkonly" style="color: rgb(5, 99, 193);">here</a></i></span><i>. If
you’re a postdoc interested in giving a SLAAM talk, we invite you to register your interest on that webform.</i></div>
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<p style="margin: 0in;"><span style="font-size: 13px;"> </span></p>
<div style="margin: 0in; font-size: 9.75pt;">Alexandra Tayar</div>
<div style="margin: 0in; font-size: 9.75pt;">Assistant Professor</div>
<div style="margin: 0in; font-size: 13px;">Department of chemical and biological physics</div>
<div style="margin: 0in; font-size: 9.75pt;">Weizmann Institute of science</div>
<div style="margin: 0in;"><a href="https://www.weizmann.ac.il/chembiophys/tayar/home" id="OWA6428e5a5-5508-22ef-71f0-6c035852c772" class="OWAAutoLink" data-auth="NotApplicable" data-loopstyle="linkonly">Tayar Lab</a><span style="font-size: 9.75pt;"> </span></div>
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